C#语言winform用webclient上传图片到python写的服务器上，一直返回404

如题，url地址确认了没有问题，但是一直都是服务器未响应404，非常奇怪
源码如下
WebClient wc = new WebClient();
wc.Credentials = CredentialCache.DefaultCredentials;
FileStream fs = new FileStream(resultfile, FileMode.Open, System.IO.FileAccess.Read, FileShare.ReadWrite);
Bitmap bm = new Bitmap(fs);
int streamlength = (int)fs.Length;
byte[] image = new byte[streamlength];
fs.Read(image, 0, streamlength);

                string strRequest = "http://guanjia.51xueba.cn:2014/upload";
                //string strRequest = "http://" + Login.URL + ":2014/upload/";

                wc.UploadFile(strRequest, resultfile);

我后面吧uploadfile换成其他方法，例如Stream postStream = wc.OpenWrite(strRequest,"put");
if (postStream.CanWrite)
{
postStream.Write(image, 0, image.Length);

                    postStream.Close();
                    fs.Dispose();
                }

也还是不行，向大神请教！